Technique identifies T cells primed for certain allergies or infections

Researchers develop a method to isolate and sequence the RNA of T cells that react to a specific target. Anne Trafton | MIT News OfficeNovember 19, 2019 When your immune system is exposed to a vaccine, an allergen, or an infectious microbe, subsets of T cells that can recognize a foreign intruder leap into action. […]

Researchers discover how cells know their future and forget their past

NOVEMBER 7, 2019 by University of Copenhagen Stem cells all share the potential of developing into any specific cell in the body. Many researchers are therefore trying to answer the fundamental questions of what determines the cells’ developmental fate as well as when and why the cells lose the potential of developing into any cell. Now, […]

Implantable cancer traps could provide earlier diagnosis, help monitor treatment

OCTOBER 29, 2019 by University of Michigan Invasive procedures to biopsy tissue from cancer-tainted organs could be replaced by simply taking samples from a tiny “decoy” implanted just beneath the skin, University of Michigan researchers have demonstrated in mice. These devices have a knack for attracting cancer cells traveling through the body. In fact, they can even pick […]

New synthesis method yields degradable polymers

Materials could be useful for delivering drugs or imaging agents in the body; may offer alternative to some industrial plastics. Anne Trafton | MIT News OfficeOctober 28, 2019 MIT chemists have devised a way to synthesize polymers that can break down more readily in the body and in the environment. A chemical reaction called ring-opening […]

Cell stiffness may indicate whether tumors will invade

Study shows tumors with softer, larger cells at their periphery are more likely to spread; may suggest new route for cancer therapy. Jennifer Chu | MIT News OfficeOctober 21, 2019 Engineers at MIT and elsewhere have tracked the evolution of individual cells within an initially benign tumor, showing how the physical properties of those cells […]

Whitehead Institute team resolves structure of master growth regulator

New research reveals how mTORC1 docks at lysosomal surface. Nicole Davis | Whitehead InstituteOctober 18, 2019 A team of Whitehead Institute scientists has for the first time revealed the molecular structure of a critical growth regulator bound to its partner proteins, creating a fine-grained view of how they interact to sense nutrient levels and control […]

Drug that blocks blood vessel growth could treat rare sarcomas

An experimental targeted drug could treat a rare type of cancer usually affecting the limbs, a clinical trial led by The Institute of Cancer Research, London, has shown. OCTOBER 16, 2019 by Institute of Cancer Research The important trial could lead to a much-needed new treatment for patients with alveolar soft part sarcoma (ASPS), which tends […]

New method visualizes groups of neurons as they compute

Fluorescent probe could allow scientists to watch circuits within the brain and link their activity to specific behaviors. Anne Trafton | MIT News OfficeOctober 9, 2019 Using a fluorescent probe that lights up when brain cells are electrically active, MIT and Boston University researchers have shown that they can image the activity of many neurons […]