Biological engineer Paul Blainey creates new tools to advance biomedical research

His technology platforms have benefited genomics, diagnostics, and drug screening. Anne Trafton | MIT News OfficeOctober 19, 2019 Microfluidics — the science of manipulating tiny amounts of fluid through channels — has been widely used in fields such as genomics, where it has helped to enable high-speed sequencing. Several years ago, Paul Blainey started to […]

Whitehead Institute team resolves structure of master growth regulator

New research reveals how mTORC1 docks at lysosomal surface. Nicole Davis | Whitehead InstituteOctober 18, 2019 A team of Whitehead Institute scientists has for the first time revealed the molecular structure of a critical growth regulator bound to its partner proteins, creating a fine-grained view of how they interact to sense nutrient levels and control […]

Imaging combined with genetic screening of cells enhances genomic discoveries

New image-based genetic screening method helps researchers identify key regulators of inflammation. Namrata Sengupta | Broad InstituteOctober 17, 2019 The following press release was issued today by the Broad Institute of MIT and Harvard. Scientists routinely use genetic screens to perturb, or change the activity of, genes in mammalian cells, one at a time, to […]

Columbia Scientists Demonstrate Power of High-Speed Microscope to Illuminate Biology at the Speed of Life

New SCAPE 2.0 system can serve as a critical tool to advance science and medicine September 27, 2019 New York | Columbia University News The Columbia team behind the revolutionary 3D SCAPE microscope announces today a new version of this high-speed imaging technology. In collaboration with scientists from around the world, they used SCAPE 2.0 […]